new modalities to evaluate histopathology, such as imaging the entire slide, has been validated in the field of dermatopathology but often are not feasible and is not available in developing countries. Many are available worldwide, the mobile phone camera technology is a potentially simple and cheap method of imaging histological slides through the use of mobile camera microscope adapter.

This study aims to validate the use of an adapter that is available commercially in the diagnosis of inflammatory conditions and infections in dermatopathology. Representative images are taken from a slide to fifty-four cases by using an adapter and share through a cloud-based platform with five dermatopathologists given the diagnosis and assess the quality of the image.

After a washout period of 8 weeks, the same case assessed by dermatopathologists together using the original glass slide. Intraobserver level of concordance was 93.3%, and the image quality cell phone was rated as “excellent” or “diagnostic” in 94.4% of cases. This study validates the use of these low-tech and inexpensive adapter as a reliable tool in teledermatopathology. Study limitations include attached to an adapter and a limited panel of diagnosis. The main value of this device may be in developing countries, but the practicality and ease of use lends itself to use in academic settings and consultation in developed countries as well.

Natural History Museum, London (NHM) has embarked on an ambitious program to digitize its collection. One objective of this program is to improve workflow and infrastructure needed to support high-throughput digitizing and creating a comprehensive digital inventory of great scientific collections. This paper presents a workflow developed to digitize the entire Phthiraptera (parasitic lice) microscope slide collection (70 663 slides). Here we describe a new process of mass digitization semi-automatic use both temporary and permanent barcode label applied before and during imaging slide.

By using a series of barcode encoding the information associated with each slide (ie a unique identifier, location in the collection and taxonomic names), we can run a series of automated processes, including renaming files, image processing and bulk import into NHM collection management systems. We provide comparative data on the efficiency of this process, illustrates how simple activities, such as automatic file renaming, reducing image post-processing time, minimizing human error and can be applied in several types of collections.

HPV E6 / E7, hTERT, and Ki67 mRNA RT-qPCR Assay for Detecting High-Grade Cervical lesions with Microscope Slides.

After breast and colon cancer, cervical cancer is the third most common cancer of women worldwide. Since the human papillomavirus (HPV) is known as the main cause of cervical cancer, HPV screening molecules when used together with cytology and histology method for the diagnosis of precancerous.

However, the HPV test’s sensitivity is currently less than 80%; thus, many cases of cervical cancer are not able to be diagnosed with HPV screening alone, and also, patients with cervical cancer are often determined to be HPV-negative with current screening methods.

Gelatin-coated microscope slides (75 x 25 mm)
PO101	FD Neurotechnologies	100 slides	EUR 186.41
Description: Best quality products

Gelatin-coated microscope slides (75 x 50 mm)
PO105	FD Neurotechnologies	100 slides	EUR 334.25
Description: Best quality products

100-place microscope slide box (for 75 x 25 mm slides)
PO201	FD Neurotechnologies	each	EUR 67.03
Description: Best quality products

25-place microscope slide box (for 75 x 25 mm slides)
PO202	FD Neurotechnologies	each	EUR 59.1
Description: Best quality products

100-place microscope slide box (for 75 x 50 mm slides)
PO203	FD Neurotechnologies	each	EUR 114.36
Description: Best quality products

Microscope slide dispenser for box of 72 standard 25 x 75mm slides
M7100-SD	MTC Bio	1/pack	EUR 69.91
Description: Microscope slide dispenser

Microscope slides, positive charged, 45° corners, frosted on one end, 25 x 75mm
M7100-45	MTC Bio	72/pack	EUR 62.83
Description: Microscope slides positive charged

Microscope slides, positive charged, 90° corners, frosted on one end, 25 x 75mm
M7100-90	MTC Bio	72/pack	EUR 62.83
Description: Microscope slides positive charged

Proteinase
HY-B2228	MedChemExpress	1g	EUR 119

Positive control tissue section for each antibody; Based on availability INQUIRE
Control-Slides	Innovex	Set of 5	EUR 176

ReadiUse™ microscope mounting solution
20009	AAT Bioquest	50 mL	EUR 115
R-phrase: R20, R21, R22 H-Phrase: H303, H313, H333 Symbol for dangerous compounds: Xn UNSPEC Code: 12352200

Amyloid (Control Slides)
TCS0003-100	ScyTek Laboratories	100 Slides	EUR 706

Amyloid (Control Slides)
TCS0003-25	ScyTek Laboratories	25 Slides	EUR 232

Amyloid (Control Slides)
TCS0003-5	ScyTek Laboratories	5 Slides	EUR 98

Argentaffin (Control Slides)
TCS0004-100	ScyTek Laboratories	100 Slides	EUR 706

Argentaffin (Control Slides)
TCS0004-25	ScyTek Laboratories	25 Slides	EUR 232

Argentaffin (Control Slides)
TCS0004-5	ScyTek Laboratories	5 Slides	EUR 98

Fungus (Control Slides)
TCS0005-100	ScyTek Laboratories	100 Slides	EUR 706

Fungus (Control Slides)
TCS0005-25	ScyTek Laboratories	25 Slides	EUR 232

Fungus (Control Slides)
TCS0005-5	ScyTek Laboratories	5 Slides	EUR 98

Bielschowsky's (Control Slides)
TCS0006-100	ScyTek Laboratories	100 Slides	EUR 706

Bielschowsky's (Control Slides)
TCS0006-25	ScyTek Laboratories	25 Slides	EUR 232

Bielschowsky's (Control Slides)
TCS0006-5	ScyTek Laboratories	5 Slides	EUR 98

Calcium (Control Slides)
TCS0007-100	ScyTek Laboratories	100 Slides	EUR 706

Calcium (Control Slides)
TCS0007-25	ScyTek Laboratories	25 Slides	EUR 232

Calcium (Control Slides)
TCS0007-5	ScyTek Laboratories	5 Slides	EUR 98

Elastic (Control Slides)
TCS0008-100	ScyTek Laboratories	100 Slides	EUR 706

Elastic (Control Slides)
TCS0008-25	ScyTek Laboratories	25 Slides	EUR 232

Elastic (Control Slides)
TCS0008-5	ScyTek Laboratories	5 Slides	EUR 98

Melanin (Control Slides)
TCS0015-100	ScyTek Laboratories	100 Slides	EUR 706

Melanin (Control Slides)
TCS0015-25	ScyTek Laboratories	25 Slides	EUR 232

Melanin (Control Slides)
TCS0015-5	ScyTek Laboratories	5 Slides	EUR 98

Mucin (Control Slides)
TCS0016-100	ScyTek Laboratories	100 Slides	EUR 706

Mucin (Control Slides)
TCS0016-25	ScyTek Laboratories	25 Slides	EUR 232

Mucin (Control Slides)
TCS0016-5	ScyTek Laboratories	5 Slides	EUR 98

Reticulum (Control Slides)
TCS0019-100	ScyTek Laboratories	100 Slides	EUR 706

Reticulum (Control Slides)
TCS0019-25	ScyTek Laboratories	25 Slides	EUR 232

Reticulum (Control Slides)
TCS0019-5	ScyTek Laboratories	5 Slides	EUR 98

Proteinase K
AR0056	BosterBio	5mL	EUR 101

Proteinase K
abx098140-1ml	Abbexa	1 ml	EUR 189
Shipped within 5-10 working days.

Proteinase K
abx082041-100mg	Abbexa	100 mg	EUR 258
Shipped within 5-10 working days.

Proteinase K
BIO-37037	Bioline	100mg	Ask for price

Proteinase K
BIO-37039	Bioline	1000mg	Ask for price

Proteinase K
G029	ABM	1.0 ml	EUR 142

Proteinase K
GE0990-100MG	Glentham Life Sciences	100 mg	EUR 94

Proteinase K
GE0990-1G	Glentham Life Sciences	1 g	EUR 413

Proteinase K
GE0990-250MG	Glentham Life Sciences	250 mg	EUR 154

Proteinase K
GE0990-25MG	Glentham Life Sciences	25 mg	EUR 58

Proteinase K
GE0990-500MG	Glentham Life Sciences	500 mg	EUR 249

Proteinase K
K1037-1	ApexBio	1 ml	EUR 67
Description: Proteinase K is a broad-spectrum serine protease and our product is extracted from Pichia pastoris cells with cloned gene encoding Engyodontium album (Tritirachium album) endolytic protease.

Proteinase K
K1037-5	ApexBio	5 ml	EUR 108
Description: Proteinase K is a broad-spectrum serine protease and our product is extracted from Pichia pastoris cells with cloned gene encoding Engyodontium album (Tritirachium album) endolytic protease.

Proteinase K
P2180-010	GenDepot	100mg	EUR 182

Proteinase K
P2180-050	GenDepot	500mg	EUR 374

Proteinase K
P2180-100	GenDepot	1g	EUR 523

Proteinase K
Z5050002	Biochain	100 mg	EUR 171
Description: No genetic downstream application can do without the good old Proteinase K.

Microscope Slide Boxes,100-Place, Blue
LC7002-001	GenDepot	Ea	EUR 70

Microscope Slide Boxes,100-Place, Blue
LC7002-010	GenDepot	10/PK	EUR 151

Microscope Slide Boxes,100-Place, Blue
LC7002-100	GenDepot	100/CS	EUR 806

Microscope Slide Boxes,100-Place, Green
LC7003-001	GenDepot	Ea	EUR 70

Microscope Slide Boxes,100-Place, Green
LC7003-010	GenDepot	10/PK	EUR 151

Microscope Slide Boxes,100-Place, Green
LC7003-100	GenDepot	100/CS	EUR 806

Microscope Slide Boxes,100-Place, Red
LC7004-001	GenDepot	Ea	EUR 70

Microscope Slide Boxes,100-Place, Red
LC7004-010	GenDepot	10/PK	EUR 151

Microscope Slide Boxes,100-Place, Red
LC7004-100	GenDepot	100/CS	EUR 806

Microscope Slide Boxes,100-Place, Yellow
LC7005-001	GenDepot	Ea	EUR 70

Microscope Slide Boxes,100-Place, Yellow
LC7005-010	GenDepot	10/PK	EUR 151

Microscope Slide Boxes,100-Place, Yellow
LC7005-100	GenDepot	100/CS	EUR 806

Microscope Slide Boxes,100-Place, White
LC7006-001	GenDepot	Ea	EUR 70

Microscope Slide Boxes,100-Place, White
LC7006-010	GenDepot	10/PK	EUR 151

Microscope Slide Boxes,100-Place, White
LC7006-100	GenDepot	100/CS	EUR 806

Microscope Slide Boxes,25-Place, Blue
LC7007-001	GenDepot	EA	EUR 66

Microscope Slide Boxes,25-Place, Blue
LC7007-010	GenDepot	10/PK	EUR 124

Microscope Slide Boxes,25-Place, Blue
LC7007-100	GenDepot	100/CS	EUR 570

Microscope Slide Boxes,25-Place, Green
LC7008-001	GenDepot	EA	EUR 66

Microscope Slide Boxes,25-Place, Green
LC7008-010	GenDepot	10/PK	EUR 124

Microscope Slide Boxes,25-Place, Green
LC7008-100	GenDepot	100/CS	EUR 570

Microscope Slide Boxes,25-Place, Red
LC7009-001	GenDepot	EA	EUR 66

Microscope Slide Boxes,25-Place, Red
LC7009-010	GenDepot	10/PK	EUR 124

Microscope Slide Boxes,25-Place, Red
LC7009-100	GenDepot	100/CS	EUR 570

Microscope Slide Boxes,25-Place, Yellow
LC7010-001	GenDepot	EA	EUR 66

Microscope Slide Boxes,25-Place, Yellow
LC7010-010	GenDepot	10/PK	EUR 124

Microscope Slide Boxes,25-Place, Yellow
LC7010-100	GenDepot	100/CS	EUR 570

Microscope Slide Boxes,25-Place, White
LC7011-001	GenDepot	EA	EUR 66

Microscope Slide Boxes,25-Place, White
LC7011-010	GenDepot	10/PK	EUR 124

Microscope Slide Boxes,25-Place, White
LC7011-100	GenDepot	100/CS	EUR 570

CometAssay High Throughput Slides
4252-02K-01	Biotechne	100 tests	EUR 1619.4

CometAssay Alkaline Control Slides
4256-010-CC	Biotechne	10 Tests	EUR 324.4

CometAssay Neutral Control Slides
4257-010-NC	Biotechne	10 Tests	EUR 324.4

Alcian Blue (Control Slides)
TCS0002-100	ScyTek Laboratories	100 Slides	EUR 706

Alcian Blue (Control Slides)
TCS0002-25	ScyTek Laboratories	25 Slides	EUR 232

Alcian Blue (Control Slides)
TCS0002-5	ScyTek Laboratories	5 Slides	EUR 98

Helicobacter Pylori (Control Slides)
TCS0011-100	ScyTek Laboratories	100 Slides	EUR 706

Helicobacter Pylori (Control Slides)
TCS0011-25	ScyTek Laboratories	25 Slides	EUR 232

Helicobacter Pylori (Control Slides)
TCS0011-5	ScyTek Laboratories	5 Slides	EUR 98

Iron - Liver (Control Slides)
TCS0013-100	ScyTek Laboratories	100 Slides	EUR 706

Iron - Liver (Control Slides)
TCS0013-25	ScyTek Laboratories	25 Slides	EUR 232

Iron - Liver (Control Slides)
TCS0013-5	ScyTek Laboratories	5 Slides	EUR 98

Mast Cell (Control Slides)
TCS0014-100	ScyTek Laboratories	100 Slides	EUR 706

Mast Cell (Control Slides)
TCS0014-25	ScyTek Laboratories	25 Slides	EUR 232

Mast Cell (Control Slides)
TCS0014-5	ScyTek Laboratories	5 Slides	EUR 98

PAS/Glycogen (Control Slides)
TCS0017-100	ScyTek Laboratories	100 Slides	EUR 706

PAS/Glycogen (Control Slides)
TCS0017-25	ScyTek Laboratories	25 Slides	EUR 232

PAS/Glycogen (Control Slides)
TCS0017-5	ScyTek Laboratories	5 Slides	EUR 98

Trichrome - Colon (Control Slides)
TCS0021-100	ScyTek Laboratories	100 Slides	EUR 706

Trichrome - Colon (Control Slides)
TCS0021-25	ScyTek Laboratories	25 Slides	EUR 232

Trichrome - Colon (Control Slides)
TCS0021-5	ScyTek Laboratories	5 Slides	EUR 98

Trichrome - Liver (Control Slides)
TCS0022-100	ScyTek Laboratories	100 Slides	EUR 706

Trichrome - Liver (Control Slides)
TCS0022-25	ScyTek Laboratories	25 Slides	EUR 232

Trichrome - Liver (Control Slides)
TCS0022-5	ScyTek Laboratories	5 Slides	EUR 98

TOMO Slides 1 Box
TOMO100	ScyTek Laboratories	100 Slides	EUR 90

Proteinase K protein
30R-2901	Fitzgerald	500 mg	EUR 425
Description: Purified recombinant Human Proteinase K protein

Proteinase 3 protein
30-1246	Fitzgerald	100 ug	EUR 543
Description: Purified native Human Proteinase 3 protein

Proteinase 3 protein
30-AP70	Fitzgerald	200 ug	EUR 624
Description: Purified native Human Proteinase 3 protein

Proteinase 3 antibody
20R-PR037	Fitzgerald	250 ul	EUR 457
Description: Rabbit polyclonal Proteinase 3 antibody

Proteinase 3 protein
30R-AP027	Fitzgerald	100 ug	EUR 727
Description: Purified native Human Proteinase 3 protein

Human Proteinase-3
7-03490	CHI Scientific	2µg	Ask for price

Human Proteinase-3
7-03491	CHI Scientific	10µg	Ask for price

Human Proteinase-3
7-03492	CHI Scientific	1mg	Ask for price

Proteinase 3 antibody
10R-1818	Fitzgerald	100 ul	EUR 403
Description: Mouse monoclonal Proteinase 3 antibody

Proteinase K Antibody
6210-100	Biovision		EUR 294

Proteinase K Antibody
6210-30T	Biovision		EUR 146

PROTEINASE K SOLUTION
501-PK	Viagen	5 ml	EUR 152
Description: Genomic PCR Grade Proteinase K Solution

Proteinase 3 Antibody
abx020707-1mg	Abbexa	1 mg	EUR 801
Shipped within 5-10 working days.

Proteinase 3 Antibody
abx011403-100ul	Abbexa	100 ul	EUR 411
Shipped within 5-10 working days.

Proteinase-3 Enzyme
20-abx073696	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

Proteinase 3 Antibody
BF0163	Affbiotech	200ul	EUR 376
Description: Proteinase 3 antibody detects endogenous levels of total Proteinase 3.

Proteinase K Solution
BIO-37084	Bioline	5ml @ 20mg/ml	Ask for price

Proteinase K Solution
BIO-37085	Bioline	5 x 5ml @ 20mg/ml	Ask for price

proteinase 3 Antibody
abx430941-200ul	Abbexa	200 ul	EUR 384
Shipped within 1-3 working days.

Proteinase K solution
GZ5904-100ML	Glentham Life Sciences	100 ml	EUR 907

Proteinase K solution
GZ5904-25ML	Glentham Life Sciences	25 ml	EUR 349

10x Proteinase K
TG4039	TopoGen	0.5ml	EUR 134

Proteinase K - 1g
PB0451	Bio Basic	1g	EUR 556.34
Product category: Proteins/Enzymes/Proteases

Solid Block (for slides / machining)
BSW01	BenchMark	1 PC	EUR 182.23
To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Solid Block (for slides / machining)
BCM1412-BSW01	Bio Basic	1 pcs, 1 UNIT	EUR 194.34
Product category: Benchtop Equipment/Heat Baths/Heat Blocks

PROTEINASE K SOLUTION 10ML
502-PK	Viagen	10 ml	EUR 239
Description: Genomic PCR Grade Proteinase K Solution

PROTEINASE K SOLUTION 25ML
503-PK	Viagen	25 ml	EUR 502
Description: Genomic PCR Grade Proteinase K Solution

Proteinase 3 (PR3) Antibody
20-abx178187	Abbexa	EUR 1177.00 EUR 578.00	1 mg 200 ug
Please enquire.

Proteinase 3 (PR3) Antibody
20-abx100860	Abbexa	EUR 411.00 EUR 133.00 EUR 1149.00 EUR 565.00 EUR 314.00	100 ug 10 ug 1 mg 200 ug 50 ug
Shipped within 5-7 working days.

Proteinase 3 (PR3) Antibody
20-abx100861	Abbexa	EUR 425.00 EUR 133.00 EUR 1177.00 EUR 578.00 EUR 328.00	100 ug 10 ug 1 mg 200 ug 50 ug
Shipped within 5-7 working days.

Proteinase 3 (PR3) Antibody
20-abx100862	Abbexa	EUR 439.00 EUR 133.00 EUR 1247.00 EUR 592.00 EUR 328.00	100 ug 10 ug 1 mg 200 ug 50 ug
Shipped within 5-7 working days.

Proteinase 3 (PR3) Antibody
20-abx174295	Abbexa	EUR 815.00 EUR 425.00	1 mg 200 ug
Please enquire.

Proteinase 3 (PR3) Antibody
20-abx174296	Abbexa	EUR 871.00 EUR 453.00	1 mg 200 ug
Please enquire.

Proteinase 3 Antigen Protein
abx061014-100ug	Abbexa	100 ug	EUR 815
Shipped within 5-10 working days.

Proteinase 3 Blocking Peptide
BF0163-BP	Affbiotech	1mg	EUR 195

Proteinase K, 20mg/ml
P2170-002	GenDepot	2X1ml	EUR 151

Proteinase K, 20mg/ml
P2170-005	GenDepot	5X1ml	EUR 199

anti-Proteinase 3 (3B4)
LF-MA30307	Abfrontier	100 ul	EUR 486
Description: Mouse Monoclonal to Proteinase 3

Proteinase 3, Human Neutrophil
PRT35-N-100	Alpha Diagnostics	25 ug	EUR 225

PRTN3 Proteinase-3 Human
PROTP24158	BosterBio	Regular: 10ug	EUR 317
Description: PRTN3 is a natural antigen having a molecular mass of 25kDa to 32kDa due to glycosylation isoforms. PRTN3 is isolated from human peripheral blood leukocytes.

Recombinant Proteinase 3 (PR3)
4-RPB434Hu01	Cloud-Clone	EUR 503.20 EUR 238.00 EUR 1612.00 EUR 604.00 EUR 1108.00 EUR 400.00 EUR 3880.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Uniprot ID: P24158 Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. Form: Freeze-dried powder Predicted Molecular Mass (KD): 20.8kDa Isoelectric Point: 6.6
Description: Recombinant Human Proteinase 3 expressed in: E.coli

Recombinant Proteinase 3 (PR3)
4-RPB434Mu01	Cloud-Clone	EUR 332.96 EUR 192.00 EUR 973.60 EUR 391.20 EUR 682.40 EUR 286.00 EUR 2284.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Uniprot ID: Q61096 Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. Form: Freeze-dried powder Predicted Molecular Mass (KD): 26.0kDa Isoelectric Point: 6.5
Description: Recombinant Mouse Proteinase 3 expressed in: E.coli

Recombinant Proteinase 3 (PR3)
4-RPB434Ra01	Cloud-Clone	EUR 476.32 EUR 230.00 EUR 1511.20 EUR 570.40 EUR 1040.80 EUR 382.00 EUR 3628.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Uniprot ID: Q8K597 Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. Form: Freeze-dried powder Predicted Molecular Mass (KD): 26.2kDa Isoelectric Point: 7
Description: Recombinant Rat Proteinase 3 expressed in: E.coli

Methicillin-Resistant Staphylococcus Aureus Antibody
20-abx137142	Abbexa	EUR 467.00 EUR 648.00	0.5 mg 1 mg
Shipped within 5-10 working days.

MEF Feeder Cells (Neomycin-resistant)
CBA-311	Cell Biolabs	1 vial	EUR 461
Description: MEF Feeder Cells are mouse embryonic fibroblasts that allow stem cell culture without LIF. Cells must be mitotically inactivated prior to addition of stem cells. Neomycin resistant.

MEF Feeder Cells (Puromycin-resistant)
CBA-312	Cell Biolabs	1 vial	EUR 461
Description: MEF Feeder Cells are mouse embryonic fibroblasts that allow stem cell culture without LIF. Cells must be mitotically inactivated prior to addition of stem cells. Puromycin resistant.

MEF Feeder Cells (Hygromycin-resistant)
CBA-313	Cell Biolabs	1 vial	EUR 461
Description: MEF Feeder Cells are mouse embryonic fibroblasts that allow stem cell culture without LIF. Cells must be mitotically inactivated prior to addition of stem cells. Hygromycin resistant.

Water-Resistant, Traceable Flashing Timer
LE9004	GenDepot	Ea	EUR 80

Vancomycin resistant enterococci PCR kit
PCR-H487-48D	Bioingentech	50T	EUR 425.8
Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Vancomycin resistant enterococci

Vancomycin resistant enterococci PCR kit
PCR-H487-96D	Bioingentech	100T	EUR 521.5
Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Vancomycin resistant enterococci

anti-Tartrate Resistant Acid Phosphatase
YF-PA10048	Abfrontier	50 ug	EUR 363
Description: Mouse polyclonal to Tartrate Resistant Acid Phosphatase

anti-Tartrate Resistant Acid Phosphatase
YF-PA10049	Abfrontier	100 ug	EUR 403
Description: Rabbit polyclonal to Tartrate Resistant Acid Phosphatase

Therefore, the human telomerase reverse transcriptase (hTERT) and Ki67 previously identified as cancer markers tested. And cells exfoliated cervical high-grade squamous intraepithelial lesions (HSIL), the most severe precancerous lesions of cancer, which is used in this study. However, it takes a long time to collect enough specimens to perform statistical analysis.