Modern digital pathology department has evolved to produce a whole-slide image data at petabyte scale, a treasure chest unprecedented for a medical machine learning tasks. Unfortunately, most of the digital slide is not described at the level of the image, hindering the large-scale application of supervised learning. Users labeling is expensive, requires a pathologist with decades of training and responsibility exceptional clinical care.

This problem is exacerbated by the United States Food and Drug Administration ruling that the primary diagnosis must come from the slide glass rather than digital images. We present a framework of end-to-end first to solve this problem, collect the explanation nonintrusive during routine clinical pathologist working this: commodities (i) 3D-print a special microscope camera mounts are used for video recording Slide- glass-based clinical diagnostic process ; (Ii) after a routine scan the whole slide, registered video frames to digital slide; (Iii) the estimated time of motion and observations to produce spatial and temporal saliency map of the entire slide.

Demonstrating the utility of this explanation, we train a neural network convolutional that detects elevated area relevant diagnosis, then report the accuracy of 85.15% in the bladder and in the prostate 91.40%, with 75.00% accuracy during training but predicting prostate bladder, although different pathologists examine a different network. When the train in one patient but other test, AUROC in bladder was 0.79 ± 0.11 and 0.96 ± 0:04 prostate.

Cost-effective and automated acquisition of the whole slide images are obstacles to wide-scale deployment of digital pathology. In this article, the calculation of which is coupled approaches to the development of the microscope slide scanner automatically presented. Realization of the prototype device built using inexpensive optical components off-the-shelf and detailed motors.

Application of advanced prototypes for clinical diagnostic tests is shown by producing good quality digital images of malaria infected blood smears. Furthermore, the slide images obtained were processed to identify and count the number of red blood cells infected with malaria and thus to estimate the level of quantitative parasitaemia. The prototype presented will enable cost-effective deployment of slide-based testing cyto-diagnostic in endemic areas.

Boveri Research Zoological Station in Naples: The rediscovery of the original microscope slides at the University of Würzburg.

Eric Davidson wrote about Theodor Boveri: “From his own research, and perhaps most importantly, his interpretation of the public, from the underlying paradigm of modern questions to base genome of embryogenesis” (Davidson, 1985).

As luck would have it, “primary data” from the experimental work Boveri, the microscope slides prepared by him and his wife Marcella during several stays at the Zoological Station in Naples (1901-1902, 1911-1912 and 1914), survived at the University of Würzburg. More than 600 slides there and despite their age they are in surprisingly good condition.

Microscope Slide Boxes,100-Place, Green
LC7003-100	GenDepot	100/CS	EUR 967.2

Microscope Slide Boxes,100-Place, Red
LC7004-100	GenDepot	100/CS	EUR 967.2

Microscope Slide Boxes,100-Place, Yellow
LC7005-100	GenDepot	100/CS	EUR 967.2

Microscope Slide Boxes,100-Place, White
LC7006-100	GenDepot	100/CS	EUR 967.2

Microscope Slide Boxes,25-Place, Blue
LC7007-100	GenDepot	100/CS	EUR 684

Microscope Slide Boxes,25-Place, Green
LC7008-100	GenDepot	100/CS	EUR 684

Microscope Slide Boxes,25-Place, Red
LC7009-100	GenDepot	100/CS	EUR 684

Microscope Slide Boxes,25-Place, Yellow
LC7010-100	GenDepot	100/CS	EUR 684

Microscope Slide Boxes,25-Place, White
LC7011-100	GenDepot	100/CS	EUR 684

Microscope slide dispenser for box of 72 standard 25 x 75mm slides
M7100-SD	MTC Bio	1/pack	EUR 83.89
Description: Microscope slide dispenser

Gelatin-coated microscope slides (75 x 50 mm)
PO105	FD Neurotechnologies	100 slides	EUR 420

Microscope Slide Boxes,100-Place, Blue
LC7002-001	GenDepot	Ea	EUR 84

Microscope Slide Boxes,100-Place, Blue
LC7002-010	GenDepot	10/PK	EUR 181.2

Microscope Slide Boxes,100-Place, Green
LC7003-001	GenDepot	Ea	EUR 84

Microscope Slide Boxes,100-Place, Green
LC7003-010	GenDepot	10/PK	EUR 181.2

Microscope Slide Boxes,100-Place, Red
LC7004-001	GenDepot	Ea	EUR 84

Microscope Slide Boxes,100-Place, Red
LC7004-010	GenDepot	10/PK	EUR 181.2

Microscope Slide Boxes,100-Place, Yellow
LC7005-001	GenDepot	Ea	EUR 84

Microscope Slide Boxes,100-Place, Yellow
LC7005-010	GenDepot	10/PK	EUR 181.2

Microscope Slide Boxes,100-Place, White
LC7006-001	GenDepot	Ea	EUR 84

Microscope Slide Boxes,100-Place, White
LC7006-010	GenDepot	10/PK	EUR 181.2

Microscope Slide Boxes,25-Place, Blue
LC7007-001	GenDepot	EA	EUR 79.2

Microscope Slide Boxes,25-Place, Blue
LC7007-010	GenDepot	10/PK	EUR 148.8

Microscope Slide Boxes,25-Place, Green
LC7008-001	GenDepot	EA	EUR 79.2

Microscope Slide Boxes,25-Place, Green
LC7008-010	GenDepot	10/PK	EUR 148.8

Microscope Slide Boxes,25-Place, Red
LC7009-001	GenDepot	EA	EUR 79.2

Microscope Slide Boxes,25-Place, Red
LC7009-010	GenDepot	10/PK	EUR 148.8

Microscope Slide Boxes,25-Place, Yellow
LC7010-001	GenDepot	EA	EUR 79.2

Microscope Slide Boxes,25-Place, Yellow
LC7010-010	GenDepot	10/PK	EUR 148.8

Microscope Slide Boxes,25-Place, White
LC7011-001	GenDepot	EA	EUR 79.2

Microscope Slide Boxes,25-Place, White
LC7011-010	GenDepot	10/PK	EUR 148.8

Slide Box White for 25 Slides
MIC4000	Scientific Laboratory Supplies	EACH	EUR 9.69

SLIDE BOX; 100 PLACE; BLUE
HS15991A	Scientific Laboratory Supplies	EACH	EUR 16.47

Box for 25 microscope slides purple colour
DD49719	Scientific Laboratory Supplies	EACH	EUR 15.28

Box for 25 microscope slides orange colour
DD49720	Scientific Laboratory Supplies	EACH	EUR 15.28

Box for 25 microscope slides turquoise colour
DD49721	Scientific Laboratory Supplies	EACH	EUR 15.28

Slide Box Blue 100 Slides
MIC3550	Scientific Laboratory Supplies	EACH	EUR 23.14

Slide Box Green 100 Slides
MIC3552	Scientific Laboratory Supplies	EACH	EUR 21.61

Slide Box Red 100 Slides
MIC3554	Scientific Laboratory Supplies	EACH	EUR 33.97

Slide Box Yellow 100 Slides
MIC3556	Scientific Laboratory Supplies	EACH	EUR 34.43

Slide Box White 100 Slides
MIC3558	Scientific Laboratory Supplies	EACH	EUR 32.83

Slide Box Grey 100 Slides
MIC3560	Scientific Laboratory Supplies	EACH	EUR 26.79

Slide Box Polystyrene 100 Slides
MIC4012	Scientific Laboratory Supplies	EACH	EUR 24.28

Slide Box Blue 25 Slides
MIC3562	Scientific Laboratory Supplies	EACH	EUR 19.13

Slide Box Green 25 Slides
MIC3564	Scientific Laboratory Supplies	EACH	EUR 19.13

Slide Box Red 25 Slides
MIC3566	Scientific Laboratory Supplies	EACH	EUR 19.13

Slide Box White 25 Slides
MIC3570	Scientific Laboratory Supplies	EACH	EUR 19.13

Microscope Slide Box 25 ULT safe
MIC4092	Scientific Laboratory Supplies	EACH	EUR 17.62

Polystyrene box for 100 microscope slides blue colour
DD139537	Scientific Laboratory Supplies	EACH	EUR 10.49

Polystyrene box for 100 microscope slides green colour
DD139538	Scientific Laboratory Supplies	EACH	EUR 10.49

Plastic box for 100 microscope slides (blue colour)
DD37501	Scientific Laboratory Supplies	EACH	EUR 29.64

Plastic box for 100 microscope slides (red colour)
DD37503	Scientific Laboratory Supplies	EACH	EUR 29.64

Economy Slide box 100 Place BLUE
MIC3586	Scientific Laboratory Supplies	EACH	EUR 17.82

Economy Slide box 100 Place RED
MIC3588	Scientific Laboratory Supplies	EACH	EUR 17.82

Economy Slide box 100 Place WHITE
MIC3590	Scientific Laboratory Supplies	EACH	EUR 16.75

Economy Slide box 25 Place BLUE
MIC3580	Scientific Laboratory Supplies	EACH	EUR 13.32

Economy Slide box 25 Place RED
MIC3582	Scientific Laboratory Supplies	EACH	EUR 13.32

Economy Slide box 25 Place WHITE
MIC3584	Scientific Laboratory Supplies	EACH	EUR 14.02

Premium Microscope Slide Box 50-Place Cork Blue
MIC4214	Scientific Laboratory Supplies	EACH	EUR 21.27

Premium Microscope Slide Box 50-Place Cork Red
MIC4216	Scientific Laboratory Supplies	EACH	EUR 19.53

PREMIUM SLIDE BOX 100 PLACE CORK LINI
HS15994G	Scientific Laboratory Supplies	EACH	EUR 23.6

PREMIUM SLIDE BOX 25 PLACE FOAM LININ
HS15989R	Scientific Laboratory Supplies	EACH	EUR 16.99

Plastic box for 100 microscope slides (assorted colours) cork bottom
DD10197	Scientific Laboratory Supplies	PK5	EUR 83.22

FUNNEL, 75 MM, PP
6120P-75	CORNING	12/pk	EUR 48
Description: Reusable Plastics; Reusable Funnels

2 Place Microscope Slide Mailer PP Natural
MIC3172	Scientific Laboratory Supplies	PK25	EUR 37.73

Slide Box White for 50 Slides
MIC4004	Scientific Laboratory Supplies	EACH	EUR 11.53

Microscope Slide Box True North
MIC4090	Scientific Laboratory Supplies	EACH	EUR 38.19

Slide Box 25 Slide Polystyrene
MIC4066	Scientific Laboratory Supplies	EACH	EUR 12.54

2 Place Microscope Slide Mailer PP Assorted Colours
MIC3170	Scientific Laboratory Supplies	PK25	EUR 38.65

Plastic box for 50 microscope slides (blue colour)
DD37507	Scientific Laboratory Supplies	EACH	EUR 25.08

Slide Box Storage Rack 15 Place
MIC3180	Scientific Laboratory Supplies	EACH	EUR 518.7

Micrewtube Box Blue 100 Place
T350-100B	Scientific Laboratory Supplies	PK24	EUR 359.1

Premium Plain Glass Microscope Slides, 144 /pk, 1 mm thickness, 25 mm wide by 73 mm long
M-ACC-GSL9	MiTeGen	200 TIPS	EUR 65
Description: Premium Plain Glass Microscope Slides, 144 /pk, 1 mm thickness, 25 mm wide by 73 mm long

Slide Tray Singles x 20 Slides
MIC4200	Scientific Laboratory Supplies	EACH	EUR 14.61

PC Freezer Box 100-Place 133x133x50mm
ARG1720	Scientific Laboratory Supplies	PK4	EUR 94.62

Cardboard tray for 20 microscope slides
DD65205	Scientific Laboratory Supplies	EACH	EUR 15.85

PC Freezer Box 25-Place 76x76x27mm
ARG1728	Scientific Laboratory Supplies	PK4	EUR 71.82

2D PolarSafe PC Box 100-Place for 2 Cryovials
ARG1214	Scientific Laboratory Supplies	EACH	EUR 47.88

Proteinase-resistant microscope slides
PO102	FD Neurotechnologies	100 slides	EUR 236.4

Vinyl microscope slides RINZL
DD52951	Scientific Laboratory Supplies	PK144	EUR 24.62

Microscope slides, positive charged, 45° corners, frosted on one end, 25 x 75mm
M7100-45	MTC Bio	72/pack	EUR 75.4
Description: Microscope slides positive charged

Microscope slides, positive charged, 90° corners, frosted on one end, 25 x 75mm
M7100-90	MTC Bio	72/pack	EUR 75.4
Description: Microscope slides positive charged

Microscope Slide Polysine 75x25x1mm
MIC3050	Scientific Laboratory Supplies	PK72	EUR 34.66

Sulfur 75 ug/g (75 PPM) for AA and ICP 100 grams in no.2 Diesel Fuel
SDFS-75-Y	Scientific Laboratory Supplies	100ML	EUR 102.6

Etoposide (100 mM)
1043-100	Biovision		EUR 183.6

Dual-Thickness MicroMounts, box of 20 with 75 micron aperture mounts; mounted on 18 mm rods
M2-L18SP-75	MiTeGen	20 MOUNTS	EUR 112
Description: Dual-Thickness MicroMounts, box of 20 with 75 micron aperture mounts; mounted on 18 mm rods

Cardboard Freezer Box 2 100-Place + Grid
ARG1682	Scientific Laboratory Supplies	EACH	EUR 9.58

SH-PEG-OH,100
33-HE003002-100	Biochempeg	EUR 592.80 EUR 1658.40	1g 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Slide dryer attachment for 3 slides
B1000-03	Benchmark Scientific	1 PC	EUR 237.56

Superfrost® Plus microscope slides
PO103	FD Neurotechnologies	box (72 slides)	EUR 123.6

Divider for 25 tubes (for boxes 136 x 136 mm)
DD39528	Scientific Laboratory Supplies	EACH	EUR 3.65

12 X 75 MM POLYPROPYLENE CULTURE TUBE
T-1275-PP	CORNING	500/pk	EUR 92.4
Description: Micro Tubes; Screw Cap Macro Tubes - Axygen

12 X 75 MM POLYSTYRENE CULTURE TUBE.
T-1275-PS	CORNING	500/pk	EUR 93.6
Description: Micro Tubes; Screw Cap Macro Tubes - Axygen

FUNNEL, 100 MM, PP
6120P-100	CORNING	12/pk	EUR 56.4
Description: Reusable Plastics; Reusable Funnels

ATP Solution (100 mM)
2121-100	Biovision		EUR 151.2

Cardboard freezer box, hinged lid, insert for 25 snap-cap 5ml tubes, 5.25 x 5.25 x 3 inches
C2580-25	MTC Bio	5/pack	EUR 76.04

2D PolarSafe PC Box 100-Place for 3 3/4 Cryovials
ARG1216	Scientific Laboratory Supplies	EACH	EUR 47.88

30-Place cardboard slide tray
MIC4201	Scientific Laboratory Supplies	EACH	EUR 27.36

Drying Box, 100 X 40 X 10mm
DB031	Bio Basic	1 UNIT	EUR 91.32

Reservoir 1 well 100 mL (width 75 mm)
DD47179	Scientific Laboratory Supplies	PK10	EUR 33.86

Slide Rack (for 24 Slides), Stainless Steel
IMS003	ScyTek Laboratories	1 ea.	EUR 115.2

AXYGEN® 25-WELL COMB FOR USE WITH 10 CM GEL BOX, 1.0 MM THICKNESS
HGB10-25-1	CORNING	1/pk	EUR 70.8
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 25-WELL COMB FOR USE WITH 10 CM GEL BOX, 2.0 MM THICKNESS
HGB10-25-2	CORNING	1/pk	EUR 70.8
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 25-WELL COMB FOR USE WITH 20 CM GEL BOX, 1.0 MM THICKNESS
HGB20-25-1	CORNING	1/pk	EUR 82.8
Description: Lab Equipment; Axygen Branded EQ

Black box 130 x 130 x 50 mm
DD139735	Scientific Laboratory Supplies	EACH	EUR 14.82

Terumo Agani needle G 25 0.5 x 25 mm
DD050139B	Scientific Laboratory Supplies	PK100	EUR 5.93

Axygen Microtube Box 100 x 1.5/2mL - Multi-Colour Pack - 142 x 142 x 55 mm
FRE0100	Scientific Laboratory Supplies	PK5	EUR 56.43

Nucleotide Set 100mM (4 x 100 mM)
110-010	GeneOn	4 x 100 µl	EUR 67.2

Nucleotide Set 100mM (4 x 100 mM)
110-011	GeneOn	4 x 200 µl	EUR 81.6

DUROPLAN Petri dish 100 x 20 mm
217554804	Scientific Laboratory Supplies	PK10	EUR 163.02

Dntp Set 100 Mm 4 x 25Umol
28406551	Scientific Laboratory Supplies	EACH	EUR 191.52

Dntp Set 100 Mm 4 x 100Umol
28406552	Scientific Laboratory Supplies	EACH	EUR 567.72

Capto HiRes S 10 x 100 mm
29275879	Scientific Laboratory Supplies	EACH	EUR 6306.48

Capto HiRes Q 10 x 100 mm
29275881	Scientific Laboratory Supplies	EACH	EUR 6306.48

Microscope Slides Plain 1.2-1.5mm 76x26mm
MIC2154	Scientific Laboratory Supplies	PK50	EUR 3.88

Microscope Slides Plain 1.0-1.2mm 76x52mm
MIC2156	Scientific Laboratory Supplies	PK50	EUR 15.73

Axygen Culture Tube 12 x 75 mm Polypropylene
AXY2174	Scientific Laboratory Supplies	PK1000	EUR 75.24

BRAND(TM) MICROSCOPE SLIDE CUT EDGES
BR474701-2500EA	Scientific Laboratory Supplies	PK2500	EUR 175.67

DB 5.7 Single block for 8 x 25 mm vials
BLO6072	Scientific Laboratory Supplies	EACH	EUR 164.16

BRAND(TM) CAVITY SLIDES 76 X 26 MM 1.2
BR475505-50EA	Scientific Laboratory Supplies	PK50	EUR 149.91

Atp 100 Mm Sol. Wi Di 25 Um
27205601	Scientific Laboratory Supplies	EACH	EUR 74.1

Gtp 100 Mm Sol. Wi Di 25 Um
27207601	Scientific Laboratory Supplies	EACH	EUR 74.1

Square Petri dish with compartments 100 x 100 mm Sterilin
DD20009	Scientific Laboratory Supplies	PK120	EUR 216.6

Slide Holder Stainless Steel Rack (for 30 Slides)
IMS005	ScyTek Laboratories	1 ea.	EUR 96

1-Place Cardboard Slide Holders Cardboard
MIC4210	Scientific Laboratory Supplies	PK25	EUR 26.79

2-Place Cardboard Slide Holders Cardboard
MIC4212	Scientific Laboratory Supplies	PK36	EUR 55.97

Cardboard divider 64 place for R3014A box
ARG1688	Scientific Laboratory Supplies	PK12	EUR 44.35

Mini gel tubes, 7 x 2.5 x 75 mm, 8/pk
2394122	Atto	6unit	EUR 315.6

Anti-Human IgM Antibody | MM-80A
MM-80A	Immunology Consultants Laboratory	1.0 mg	EUR 334
Description: Anti-Human IgM Antibody | MM-80A | Immunology Consultants Laboratory Host: Mouse Format: Unconjugated AP Product Type: Secondary Antibody Antibody Clonality: Monoclonal

Humid Box for Metal Slide Tray
H011	Insitus Biotechnologies	each	EUR 86.4

Cryo storage box, 100 place (10 x 10), polycarbonate, with hinged lid and unique barcode
R2100	MTC Bio	5/pack	EUR 99.7
Description: Cryo storage box 100 place (10 x 10)

PAS/Glycogen, For Digestion (Control Slides)
TCS0024-25	ScyTek Laboratories	25 Slides	EUR 278.4

Sodium Pyruvate Solution, 100 mM Solution
CCM1753-100	Bio Basic	100 mL	EUR 73.01

100 mM CTAB
605	AthenaES	100 ml	EUR 117.6

Cycloheximide (100 mM)
1041-1	Biovision		EUR 170.4

dUTP (100 mM)
P033-01	Vazyme	1 ml	EUR 172.8

dATP (100 mM)
P034-01	Vazyme	1 ml	EUR 172.8

dTTP (100 mM)
P035-01	Vazyme	1 ml	EUR 172.8

dCTP (100 mM)
P036-01	Vazyme	1 ml	EUR 172.8

dGTP (100 mM)
P037-01	Vazyme	1 ml	EUR 172.8

dCTP 100 mM
FYT014-100UL	Yeastern Biotech	100 µl	Ask for price

BRAND(TM) STAINING TRAY FOR 25 SLIDES
BR471400-5EA	Scientific Laboratory Supplies	PK5	EUR 46.63

Cardboard Dividers 25-Place 67x67x32mm
ARG1684	Scientific Laboratory Supplies	PK12	EUR 38.3

DiagNano Fluorophore Labeled Gold Nanoparticles, 75 nm
GFL-75	Creative Diagnostics	1 mL	EUR 1263.6

MgCl2 25 mM
BA00154	Bioatlas	5x1.8ml	EUR 74.4
Description: High purity buffer for various PCR applications.

Cardboard divider for box 133 x 133 m height 30 mm for 10 x 10 o up to 12 mm
DD39887	Scientific Laboratory Supplies	EACH	EUR 4.56

Single channel mini-pipette (130 mm) 25 ul, autoclavable
SCMP-25	Alpha Diagnostics	1	EUR 110.4

Mini gel tubes, 7 x 2.5 x 100 mm, 8/pk
2394132	Atto	6unit	EUR 327.6

Plastic cell counting slides Kovas Slide
DD50126	Scientific Laboratory Supplies	EACH	EUR 253.08

Triton® X-100 Detergent
B2394-100	Biovision		EUR 130.8

38 Place Cold Rack Box
IB002A	Bio Basic	1 UNIT	EUR 75.66

Freezer Storage Box 81-Place
Z756628-5EA	Scientific Laboratory Supplies	PK5	EUR 67.83

Cardboard Divider for box 133 x 133 m height 65 mm for 9 x 9 tubes o up to 13.6 mm
DD39574	Scientific Laboratory Supplies	EACH	EUR 4.79

Cardboard divider for box 133 x 133 m height 30 mm for 14 x 14 tubes o up to 8.3 mm
DD39884	Scientific Laboratory Supplies	EACH	EUR 6.84

Cardboard divider for box 133 x 133 m height 30 mm for 13 x 13 tubes o up to 9 mm
DD39885	Scientific Laboratory Supplies	EACH	EUR 6.73

Cardboard divider for box 133 x 133 m height 30 mm for 12 x 12 tubes o up to 9.8 mm
DD39886	Scientific Laboratory Supplies	EACH	EUR 6.16

Cardboard divider for box 133 x 133 m height 30 mm for 8 x 8 tubes o up to 30 mm
DD39888	Scientific Laboratory Supplies	EACH	EUR 4.22

TOMO Slides 1 Box
TOMO100	ScyTek Laboratories	100 Slides	EUR 108

Freezer box - dimensions 148 x 148 x 128 mm - uncompartmented - white
DD142346	Scientific Laboratory Supplies	EACH	EUR 20.86

Star-Frost slides 76 x 26 mm (standard version) colour : orange
DD100205O	Scientific Laboratory Supplies	PK50	EUR 12.54

Cardboard Dividers 25-Place for 2 or 3 Boxes
ARG1674	Scientific Laboratory Supplies	PK12	EUR 38.3

Regular Unleaded Gasoline 75% Weathered
S-WG-75	Scientific Laboratory Supplies	1ML	EUR 221.16

COVER GLASS, NO. 1, SQUARE 25 X 25MM
2845-25	CORNING	100/pk	EUR 134.4
Description: Cover Glass; Cover Glass, CGW

COVER GLASS, NO. 2, SQUARE 25 X 25MM
2855-25	CORNING	50/pk	EUR 103.2
Description: Cover Glass; Cover Glass, CGW

Slide labeled and dated in handwriting Boveri and thus can be assigned to publish the experimental work at sea urchin development. Results Boveri allowed to reveal the role of the cell nucleus and chromosomes in the development and heritage. Here, I present an overview of the slides in the context Boveri work together with images of selected specimens taken from the original slide. It is planned to check the slide in more detail, taking high-resolution pictures a series of specimens of significant focus and make them available online.